Medically reregarded by Dena Westphalen, Pharm.D. — Written by Rachel Nall, MSN, CRNA on August 29, 2019

You are watching: Can you take pepto bismol with alcohol

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The pink liquid or pink pill of bismuth subsalicylate (generally well-known by the brand name Pepto-Bismol) have the right to relieve symptoms prefer upset stomach and diarrhea. So once you’ve overdone it on the alcohol, it may sound like a good setup for easing your stomach woes.

However before, tbelow are some factors why Pepto-Bismol and also alcohol may not mix as well as a Jack and Coke did the night before. Keep analysis for some considerations before reaching for the Pepto as soon as your stomach harms.

Pepto’s active ingredient, bismuth subsalicylate, has anti-inflammatory properties that reduce the irritation that have the right to reason diarrhea and upset stomach.

The medication also coats the stomach lining, which acts as a barrier between the stomach lining and also the substances that can irritate the stomach, such as stomach acid.

Pepto additionally has actually antimicrobial results. For this reason, medical professionals prescribe it to treat H. pyloriinfections that have the right to cause acid reflux and also upcollection stomach.

Alcohol can irritate the stomach lining and cause a symptom well-known as gastritis. The problem have the right to reason symptoms such as:

bloating food regurgitation nauseatop abdominal pain vomiting

Periodic gastritis from a night of overindulging typically isn’t that bad. However before, those who have alcohol usage disorder or frequently binge drink have the right to endure damages because of chronic inflammation in the stomach lining. This can cause ulcers and gastrointestinal (GI) bleeding.

The main factor why Pepto and alcohol don’t mix well is that the liver is (at least in part) responsible for metabolizing both alcohol and Pepto-Bismol. While the gastrointestinal tract is largely responsible for absorbing the active ingredients in Pepto-Bismol, it’s believed the liver breaks some down as well.

The potential problem through this is if the liver is as well busy breaking dvery own one drug, it might not break the other down as properly. This deserve to possibly damage the liver and likewise extfinish the amount of time both Pepto-Bismol and also alcohol are existing in the body.

Doctors likewise issue about the use of Pepto-Bismol and also alcohol if a perboy has ulcers. These are locations of the stomach that aren’t safeguarded by the stomach’s lining, and also deserve to cause pain and also bleeding. The combicountry of alcohol and also Pepto-Bismol can increase the risks for GI bleeding.

One authorize to look for

If you do usage Pepto to try and relieve your upcollection stomach while drinking or after drinking, watch your stool for symptoms of GI bleeding. This can incorporate bappropriate or dark red blood in your stool.

Pepto can revolve your stool babsence, so this readjust in shade doesn’t necessarily suppose you have a trouble.

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A lot of the potential interactions in between Pepto-Bismol and alcohol are theoretical. Tbelow aren’t many medical reports from people who’ve been hequipped by the alcohol-and-Pepto combo. But there likewise aren’t any researches in the previous few years that display taking Pepto after drinking is beneficial or safe.

Tright here are a couple of research studies from the 1990s that didn’t report side effects from using Pepto and also drinking. One from 1990 publimelted in the Journal of International Medical Research stupassed away 132 volunteers that drank to excess and took either Pepto or a placebo.

At the finish of the study, they didn’t discover any kind of side impacts from taking the medicine and drinking. The participants that took Pepto did report much better symptom relief. Aget, this is an older examine and among the few that looked at Pepto and alcohol.

A hangover is the combination of dehydration, irritation to your stomach and your body’s initiatives to clear the alcohol from your system. Unfortunately, there’s not a lot you deserve to carry out other than let time pass and your body clear the alcohol from your system.

Doctors haven’t prrange any definitive methods for curing or accelerating a hangover’s symptoms — this even has research studies on offering intravenous (IV) fluids and also taking a pain reliever before bed.


You have the right to drink water or various other electrolyte-containing beverages in an effort to re-hydrate. But drinking plenty of fluids is a healthy concept whether you have actually a hangover or not.

Eat carefully

Until you feel much better, you deserve to also eat bland also foods that aren’t most likely to upcollection your stomach further. These include:

applesauce bananasbroth simple crackers toast

Get checked after a day

If you don’t feel much better after about 24 hours, you may want to see your physician in situation your symptoms might be concerned one more medical problem.