A homologous chromosome comes to among a pair of chromosomes via the very same gene sequence, loci, chromosomal size, and also centromere place. A homologous pair consists of one paternal and also one maternal chromosome. In humans, there are a complete of 46 chromosomes in the nucleus of a somatic cell. Half of them (22 autosomes + X or Y chromosome) are inherited from the father and the various other half (22 autosomes + X chromosome), from the mommy. Each maternal chromosome has actually a matching paternal chromosome; they pair up during meiosis. Generally, a female will have 23 homologous chromosomes whereas a male will certainly have 22. That is because the sex chromosomes, X and also Y, in males are not homologous. The pairing up of homologous chromosomes throughout meiosis is important to promote genetic variation. Because of the hereditary recombicountry that occurs in between homologous pairs at meiosis, the resulting haploid gametes contain chromosomes that are genetically various from each various other. This amplifies gene pool, thereby, increasing the possibilities of getting genes essential to organic fitness and also survival.

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Homologous chromosome definition

In biology, homologous chromosomes are paired chromosomes. They basically have actually the same gene sequence, loci (gene position), centromere place, and also chromosomal size. Although they may have the very same genetic sequence and also loci, they may differ in alleles. The homologous pair is consisted of of a paternal chromosome and also a maternal chromosome. These chromosomes pair up during meiosis however not in the time of mitosis.


The term homologous came from Greek homologos, meaning “agreeing” or “of one mind”. It is a mix of homos, interpretation “same” and also logos, meaning “relation”. The term chromosome was coined in 1889 by Germale anatomist, Wilhelm von Waldeyer-Hartz. It was obtained from the Greek khrōma, interpretation “color” since it readily stained through fundamental dyes. Synonym: homologue.

Homologous chromosomes vs. heterologous chromosomes

When chromosomes are homologous, it implies that they are the same, at leastern in regards to the gene sequences and loci. Heterologous, in essence, indicates “different”. This suggests that heterologous (non-homologous) chromosomes would certainly, therefore, pertain to any type of two chromosomes that are different, such as in terms of gene sequence and also loci. Throughout meiosis, homologous chromosomes might normally exreadjust hereditary material. Heterologous chromosomes execute not. However, there are instances wherein heterologous chromosomes perform exreadjust chromosomal components. When this occurs, the procedure is called chromosomal translocation. It is a kind of mutation that can result in serious chromosomal aberrations. For the comparikid between homologous chromosomes and also heterologous chromosomes, check out table below.

Homologous chromosomes have actually alleles on the exact same genes located in the very same loci. Heterologous chromosomes have actually alleles on various genes.
Pairs up during meiosis Does not pair up throughout meiosis
Gene extransforms may happen at synapse. Gene exalters might happen at translocation.
Basic parts:

centromere (kinetochore) lengthy arms (q) brief arms (p)
Basic parts:

centromere (kinetochore) lengthy arms (q) brief arms (p)

22 autosomal chromosomes XX sex chromosomes

XY sex chromosome Any chromosome that supposedly belongs to a chromosomal pair

Homologous chromosome vs. sister chromatids

At meiosis, each of the homologous chromosomes is comprised of two the same chromatids joined together by a common kinetochore (centromere). The the same chromatids are specifically called sister chromatids to identify them from the so-referred to as non-sister chromatids. Prior to cell divisions, the chromosomes in the nucleus show up as threadchoose strands (dubbed chromatins). When a cell is fated to undergo mitosis or meiosis, they condense right into thicker structures. By this time, the chromatin is described as a chromosome. The DNA in the chromosome replicates by DNA replication throughout the S phase of the interphase. After replicating, tright here would have actually been 2 DNA copies, each present in a strand referred to as chromatid. The two chromatids joined by a prevalent centromere are referred to as sister chromatids. The chromatids of the various other member of a homologous pair are referred to as non-sister chromatids.


Homologous chromosomes mirroring sister and non-sister chromatids. Genetic recombination have the right to happen in between non-sister chromatids.

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The chromosomes of a eukaryotic cell are located in the nucleus. The chromosomes in the nucleus are of two sets. One collection would certainly come from the male gamete (sperm cell) and also the other set, from the female gamete (egg cell). Prior to fertilization, both gametes are haploid. When the sperm cell effectively fertilizes the egg cell the resulting zygote is a diploid, which means the union of the 2 haploid cells outcomes in a single cell through 2 sets of chromosomes: one collection that is maternally-acquired and another set that is paternally-acquired. Each maternal chromosome has a corresponding paternal chromosome of the same gene sequence, gene loci, chromosomal size, and centromere area. The pair comes close to each various other throughout meiosis so that they can exadjust genes between sister and also non-sister chromatids. Although both members of the homologous pair have actually equivalent genes and also loci, they might differ in the alleles. For example, both of them carry genes coding for the eye color trait. One has actually alleles for the brown-eye trait whereas the other, for the blue-eye trait. In this case, the alleles are various and also the homologous chromosomes are defined as heterozygous. On the contrary, once the alleles are the exact same (e.g. both alleles for the very same gene code for the blue-eye trait) then, they are sassist to be homozygous. The meaning of alleles was demonstrated by Gregor Mendel via his pioneering functions in genetics using garden peas. He had the ability to present that among the alleles might be dominant over the other. In this instance, just one allele will be expressed. A trait demonstrating this pattern is described as Mendelian inheritance. Nevertheless, in people, hereditary expressions are not straightforward. Many kind of of the huguy traits execute not condevelop to the Mendelian pattern of inheritance. In this regard, they are referred to as non-Mendelian.

Homologous chromosomes Maternal chromosome Paternal chromosome Inherited from the mom Inherited from the father Same genetic sequence, loci, chromosomal length, and centromere area Alleles may be the same or different

Pairing process

Meiosis is a kind of cell department wherein diploid organisms halve their variety of chromosomes and also homologous chromosomes pair up. In contrast, mitosis (an additional develop of cell division) results in 2 daughter cells, each containing the exact same chromosomal number as the parent cell. In meiosis, a diploid (2n) cell will provide rise to four haploid (n) cells. The cells that undergo meiosis are the gametes creating haploid sperm cell and also egg cell. Haploidy is essential so that at fertilization the chromosomal number continues to be the same throughout generations. In order to accomplish haploidy, the cell undergoes 2 consecutive nuclear divisions. They are described as meiosis I and meiosis II. To prepare the cell to meiosis, one of the significant preparatory steps is DNA replication. The chromosomes duplicate their DNA, especially in the S phase of interphase. At this suggest, each of the chromosomes will certainly consist of 2 strands (sister chromatids) joined at the centromere. The pairing (synapse) of homologous chromosomes will occur at prophase I. DNA exchanges happen in between homologous chromosomes using homologous recombination and crossover at chiasmata between non-sister chromatids. Then, the homologous pairs line up at the metaphase plate. Next, the homologous chromosomes separate during anaphase I and relocate to the opposite poles of the cell. Then, the cell divides for the initially time throughout telophase I bring about two genetically non-identical daughter cells but with sister chromatids still undamaged. Each cell will certainly undergo meiosis II so that the resulting daughter cells will each have actually a chromosomal number lessened by fifty percent.

Human being karyotype


The homologous chromosomes of people based on the gene sequences, loci, and also centromere area. A somatic cell (2n) contains 46 chromosomes and also 22 of them are homologous. If the sex chromosomes are both X chromosomes, then the complete number of homologous chromosomes is 23.

In humans, the nucleus frequently has 46 chromosomes. Thus, there are 22 pairs of autosomes through about the very same length, staining pattern, and genes through the exact same loci. As for the sex chromosomes, the 2 X chromosomes are taken into consideration as homologous whereas the X and Y chromosomes are not. Thus, females have actually 23 homologous chromosomes (i.e. 22 autosomes + 1 X-X chromosomes) whereas males have actually only 22.


The chromosomes are crucial to all living things because they lug the genetic instructions for all of the cell’s tasks. They also bear the hereditary information that determines the trait of an organism. Homologous chromosomes, therefore, are necessary in the exact same way. They lug genetic indevelopment that has actually been passed dvery own from one generation to the next. And given that alleles might maybe be different in the very same gene, the outcome is differing phenotypes. Hence, the distinctiveness of an individual of the very same species is established. Acomponent from this, the organism is capable of reproducing offspring that is genetically various from itself and from the rest of its descendants. The homologous chromosomes in the nucleus of the organism’s gamete pair up during meiosis. This occasion is vital to promote hereditary variation. The homologous pair exalters genes via genetic recombination so that hereditary diversity might be supported. This is pertained to as one of the benefits of having actually been able to recreate sexually. Those that recreate asexually produce a clone of themselves. Thus, this could reduce the gene pool. A tiny gene pool implies low hereditary diversity. It can be unfavorable bereason it indicates there is much less opportunity in acquiring genes important for adapting to an environment at risk to inexorable physicochemical changes. In comparison, better genetic varicapacity indicates a higher propensity to get better genes. High genetic diversity likewise implies a large gene pool. This, subsequently, implicates raised chances of gaining genes that can boost organic fitness and also survival.

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